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BMCBI
2006
101views more  BMCBI 2006»
13 years 9 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
WSCG
2003
155views more  WSCG 2003»
13 years 11 months ago
Optimal Curve Fitting to Digital Data
An optimal curve fitting technique has been developed which is meant to automatically provide a fit to any ordered digital data in plane. A more flexible class of rational cubic f...
Muhammad Sarfraz
ERSHOV
1999
Springer
14 years 1 months ago
Binding-Time Analysis in Partial Evaluation: One Size Does Not Fit All
Abstract. Existing partial evaluators usually fix the strategy for binding-time analysis. But a single strategy cannot fulfill all goals without leading to compromises regarding ...
Niels H. Christensen, Robert Glück, Sø...
CHI
2003
ACM
14 years 10 months ago
Combined model for text entry rate development
We combine the power law of learning and theoretical upper limit predictions to describe the development of text entry rates from users' first contact to asymptotic expert us...
Poika Isokoski, I. Scott MacKenzie
BMCBI
2010
156views more  BMCBI 2010»
13 years 9 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...