Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
We describe SVMotif, a support vector machine-based learning algorithm for identification of cellular DNA transcription factor (TF) motifs extrapolated from known TF-gene interact...
Mark A. Kon, Yue Fan, Dustin T. Holloway, Charles ...
Background: Computational biologists use Expectation values (E-values) to estimate the number of solutions that can be expected by chance during a database scan. Here we focus on ...
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Existing web usage mining techniques focus only on discovering knowledge based on the statistical measures obtained from the static characteristics of web usage data. They do not ...