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BMCBI
2004
177views more  BMCBI 2004»
13 years 8 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
ICMLA
2007
13 years 10 months ago
SVMotif: A Machine Learning Motif Algorithm
We describe SVMotif, a support vector machine-based learning algorithm for identification of cellular DNA transcription factor (TF) motifs extrapolated from known TF-gene interact...
Mark A. Kon, Yue Fan, Dustin T. Holloway, Charles ...
BMCBI
2005
93views more  BMCBI 2005»
13 years 8 months ago
Computing expectation values for RNA motifs using discrete convolutions
Background: Computational biologists use Expectation values (E-values) to estimate the number of solutions that can be expected by chance during a database scan. Here we focus on ...
André Lambert, Matthieu Legendre, Jean-Fred...
ISMB
2000
13 years 10 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa
CIKM
2005
Springer
14 years 2 months ago
WAM-Miner: in the search of web access motifs from historical web log data
Existing web usage mining techniques focus only on discovering knowledge based on the statistical measures obtained from the static characteristics of web usage data. They do not ...
Qiankun Zhao, Sourav S. Bhowmick, Le Gruenwald