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RECOMB
2010
Springer
15 years 6 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
FMSB
2008
129views Formal Methods» more  FMSB 2008»
15 years 6 months ago
Rule-Based Modelling, Symmetries, Refinements
Rule-based modelling is particularly effective for handling the highly combinatorial aspects of cellular signalling. The dynamics is described in terms of interactions between part...
Vincent Danos, Jérôme Feret, Walter F...
AIPS
2003
15 years 6 months ago
A Multi-Agent System-driven AI Planning Approach to Biological Pathway Discovery
As genomic and proteomic data is collected from highthroughput methods on a daily basis, subcellular components are identified and their in vitro behavior is characterized. Howev...
Salim Khan, William Gillis, Carl Schmidt, Keith De...
DICTA
2003
15 years 6 months ago
Segmentation by Adaptive Prediction and Region Merging
Abstract This paper presents a segmentation technique based on prediction and adaptive region merging. While many techniques for segmentation exist, few of them are suited for the ...
Marc Van Droogenbroeck, Hugues Talbot
NIPS
1998
15 years 6 months ago
An Entropic Estimator for Structure Discovery
We introduce a novel framework for simultaneous structure and parameter learning in hidden-variable conditional probability models, based on an entropic prior and a solution for i...
Matthew Brand
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