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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 7 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BCB
2010
213views Bioinformatics» more  BCB 2010»
13 years 2 months ago
Markov clustering of protein interaction networks with improved balance and scalability
Markov Clustering (MCL) is a popular algorithm for clustering networks in bioinformatics such as protein-protein interaction networks and protein similarity networks. An important...
Venu Satuluri, Srinivasan Parthasarathy, Duygu Uca...
RECOMB
2005
Springer
14 years 7 months ago
Decomposition of Overlapping Protein Complexes: A Graph Theoretical Method for Analyzing Static and Dynamic Protein Associations
Background: Most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complex...
Elena Zotenko, Katia S. Guimarães, Raja Jot...
ISMB
2000
13 years 8 months ago
Search for a New Description of Protein Topology and Local Structure
A novel description of protein structure in terms of the generalized secondary structure elements (GSSE) is proposed. GSSE's are defined as fragments of the protein structure...
Lukasz Jaroszewski, Adam Godzik
BMCBI
2006
133views more  BMCBI 2006»
13 years 7 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen