We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
One of the main goals in the analysis of microarray data is to identify groups of genes and groups of experimental conditions (including environments, individuals, and tissues) tha...
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
In this work, we address the biclustering of gene expression data with evolutionary computation, which has been proven to have excellent performance on complex problems. In express...