Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Background: Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecula...
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Background: High-throughput methods identify an overwhelming number of protein-protein interactions. However, the limited accuracy of these methods results in the false identifica...
An important problem in the area of homeland security is to identify abnormal or suspicious entities in large datasets. Although there are methods from data mining and social netwo...