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BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
CNstream: A method for the identification and genotyping of copy number polymorphisms using Illumina microarrays
Background: Understanding the genetic basis of disease risk in depth requires an exhaustive knowledge of the types of genetic variation. Very recently, Copy Number Variants (CNVs)...
Arnald Alonso, Antonio Julià, Raül Tor...
BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
Prodigal: prokaryotic gene recognition and translation initiation site identification
Background: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the num...
Doug Hyatt, Gwo-Liang Chen, Philip F. LoCascio, Mi...
BMCBI
2010
161views more  BMCBI 2010»
13 years 7 months ago
FRASS: the web-server for RNA structural comparison
Background: The impressive increase of novel RNA structures, during the past few years, demands automated methods for structure comparison. While many algorithms handle only small...
Svetlana Kirillova, Silvio C. E. Tosatto, Oliviero...
BMCBI
2010
99views more  BMCBI 2010»
13 years 7 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
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