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BMCBI
2006
13 years 7 months ago
2006
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
BMCBI
2006
13 years 7 months ago
2006
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
BMCBI
2006
13 years 7 months ago
2006
Background: Cluster analysis is an integral part of high dimensional data analysis. In the context of large scale gene expression data, a filtered set of genes are grouped togethe...
BMCBI
2006
13 years 7 months ago
2006
Background: Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique ha...
BMCBI
2006
13 years 7 months ago
2006
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...