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BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
BMCBI
2005
98views more  BMCBI 2005»
13 years 7 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
TJS
2008
105views more  TJS 2008»
13 years 7 months ago
Using a relational database for scalable XML search
XML is a flexible and powerful tool that enables information and security sharing in heterogeneous environments. Scalable technologies are needed to effectively manage the growing...
Rebecca Cathey, Steven M. Beitzel, Eric C. Jensen,...
BMCBI
2005
113views more  BMCBI 2005»
13 years 7 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
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