The main objectives of cancer treatment in general, and of cancer chemotherapy in particular, are to eradicate the tumour and to prolong the patient survival time. Traditionally, t...
This paper presents a methodology for using heuristic search methods to optimise cancer chemotherapy. Specifically, two evolutionary algorithms - Population Based Incremental Lear...
Andrei Petrovski, Siddhartha Shakya, John A. W. Mc...
Abstract-- Cancer treatment by chemotherapy involves multiple applications of toxic drugs over a period of time. Optimising the schedule of these treatments can improve the outcome...
Cancer chemotherapy is a complex treatment mode that requires balancing the benefits of treating tumours using anti-cancer drugs with the adverse toxic side-effects caused by these...
Andrei Petrovski, Bhavani Sudha, John A. W. McCall
The toxicity of an anticancer drug is cleared from the body by different processes, including saturable metabolic and nonsaturable renal-excretion pathways. According to the princ...