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BMCBI
2010
86views more  BMCBI 2010»
13 years 9 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
LREC
2008
118views Education» more  LREC 2008»
13 years 10 months ago
Evaluation of several Maximum Likelihood Linear Regression Variants for Language Adaptation
Multilingual Automatic Speech Recognition (ASR) systems are of great interest in multilingual environments. We studied the case of the Comunitat Valenciana where the two official ...
Míriam Luján-Mares, Carlos D. Mart&i...
SIGIR
2002
ACM
13 years 8 months ago
Two-stage language models for information retrieval
The optimal settings of retrieval parameters often depend on both the document collection and the query, and are usually found through empirical tuning. In this paper, we propose ...
ChengXiang Zhai, John D. Lafferty
BMCBI
2010
167views more  BMCBI 2010»
13 years 9 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BMCBI
2011
13 years 13 days ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf