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» Multiclass discovery in array data
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BMCBI
2010
103views more  BMCBI 2010»
13 years 11 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
BMCBI
2006
110views more  BMCBI 2006»
13 years 11 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
BMCBI
2010
99views more  BMCBI 2010»
13 years 11 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
BMCBI
2010
96views more  BMCBI 2010»
13 years 11 months ago
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
Background: Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) or ChIP followed by genome tiling array analysis (ChIP-chip) have become standar...
Lihua J. Zhu, Claude Gazin, Nathan D. Lawson, Herv...
ITS
1998
Springer
213views Multimedia» more  ITS 1998»
14 years 3 months ago
Component-Based Construction of a Science Learning Space
We present a vision for learning environments, called Science Learning Spaces, that are rich in engaging content and activities, provide constructive experiences in scientific proc...
Kenneth R. Koedinger, Daniel D. Suthers, Kenneth D...