Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Background: One of the strategies for protein function annotation is to search particular structural motifs that are known to be shared by proteins with a given function. Results:...
Background: It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not ...
Lachlan James M. Coin, Alex Bateman, Richard Durbi...