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RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
BMCBI
2005
102views more  BMCBI 2005»
13 years 7 months ago
Modelling the interaction of steroid receptors with endocrine disrupting chemicals
Background: The organic polychlorinated compounds like dichlorodiphenyltrichloroethane with its metabolites and polychlorinated biphenyls are a class of highly persistent environm...
Pasqualina D'Ursi, Erika Salvi, Paola Fossa, Lucia...
BMCBI
2006
160views more  BMCBI 2006»
13 years 7 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
DEXAW
2004
IEEE
80views Database» more  DEXAW 2004»
13 years 11 months ago
Traceable Document Flows
Ad-hoc data exchange, e.g., by sending email attachments, leads to multiple copies or versions of a document at dispersed nodes in a network. However, their relationships such as ...
Martin Bernauer, Gerti Kappel, Elke Michlmayr
RECOMB
1999
Springer
13 years 11 months ago
Evolution of metabolisms: a new method for the comparison of metabolic pathways
The abundance of information provided by completely sequenced genomes de nes a starting point for new insights in the multilevel organization of organisms and their evolution. At ...
Christian V. Forst, Klaus Schulten