Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
- This article introduces a novel protein structure alignment method (named TALI) based on protein backbone torsion angle instead of the more traditional distance matrix. Represent...
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
During the last few years new functionalities of RNA have been discovered, renewing the need for computational tools for their analysis. To this respect, multiple sequence alignmen...