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155
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BMCBI
2008
178views more  BMCBI 2008»
15 years 3 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
149
Voted
BMCBI
2008
130views more  BMCBI 2008»
15 years 3 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
146
Voted
ICASSP
2011
IEEE
14 years 7 months ago
Iterative estimation of structures of multiple RNA homologs: Turbofold
TurboFold, an iterative algorithm for estimating the common secondary structures of multiple RNA homologs, is presented. The algorithm is motivated by and has structure and attrib...
Gaurav Sharma, Arif Ozgun Harmanci, David H. Mathe...
102
Voted
CANDC
2006
ACM
15 years 3 months ago
Domain boundary prediction based on profile domain linker propensity index
Successful prediction of protein domain boundaries provides valuable information not only for the computational structure prediction of multidomain proteins but also for the exper...
Qiwen Dong, Xiaolong Wang, Lei Lin, Zhiming Xu
139
Voted
ACL
2010
15 years 1 months ago
Learning Script Knowledge with Web Experiments
We describe a novel approach to unsupervised learning of the events that make up a script, along with constraints on their temporal ordering. We collect naturallanguage descriptio...
Michaela Regneri, Alexander Koller, Manfred Pinkal