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» Multiple RNA Structure Alignment
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BMCBI
2006
130views more  BMCBI 2006»
13 years 8 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...
BMCBI
2004
126views more  BMCBI 2004»
13 years 8 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
BMCBI
2008
244views more  BMCBI 2008»
13 years 8 months ago
RNAalifold: improved consensus structure prediction for RNA alignments
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
Stephan H. F. Bernhart, Ivo L. Hofacker, Sebastian...
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
14 years 1 months ago
Conserved RNA Pseudoknots
: Pseudoknots are essential for the functioning of many small RNA molecules. In addition, viral RNAs often exhibit pseudoknots that are required at various stages of the viral life...
C. Thurner, Ivo L. Hofacker, Peter F. Stadler