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» Multiple Sequence Alignment System for Pyrosequencing Reads
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IPPS
2006
IEEE
14 years 1 months ago
Parallel implementation and performance characterization of MUSCLE
Multiple sequence alignment is a fundamental and very computationally intensive task in molecular biology. MUSCLE, a new algorithm for creating multiple alignments of protein sequ...
Xi Deng, Eric Li, Jiulong Shan, Wenguang Chen
RECOMB
2003
Springer
14 years 8 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
14 years 2 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
NAR
2007
109views more  NAR 2007»
13 years 7 months ago
GeneTrees: a phylogenomics resource for prokaryotes
The GeneTrees phylogenomics system pursues comparative genomic analyses from the perspective of gene phylogenies for individual genes. The GeneTrees project has the goal of provid...
Yuying Tian, Allan W. Dickerman
TCBB
2008
95views more  TCBB 2008»
13 years 7 months ago
Solving the Problem of Trans-Genomic Query with Alignment Tables
Abstract-- The trans-genomic query (TGQ) problem -- enabling the free query of biological information, even across genomes -- is a central challenge facing bioinformatics. Solution...
Douglas Stott Parker Jr., Ruey-Lung Hsiao, Yi Xing...