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NAR
1998
86views more  NAR 1998»
13 years 9 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
BMCBI
2008
163views more  BMCBI 2008»
13 years 10 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
GECCO
2007
Springer
160views Optimization» more  GECCO 2007»
14 years 4 months ago
A memetic algorithm for the low autocorrelation binary sequence problem
Finding binary sequences with low autocorrelation is a very hard problem with many practical applications. In this paper we analyze several metaheuristic approaches to tackle the ...
José E. Gallardo, Carlos Cotta, Antonio J. ...
NAACL
2010
13 years 8 months ago
Prenominal Modifier Ordering via Multiple Sequence Alignment
Producing a fluent ordering for a set of prenominal modifiers in a noun phrase (NP) is a problematic task for natural language generation and machine translation systems. We prese...
Aaron Dunlop, Margaret Mitchell, Brian Roark
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
14 years 3 months ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye