Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Microarray technologies have allowed the measurement of expression of multiple genes simultaneously. Gene expression levels can be used to classify tissues into diagnostic or progn...
Lucila Ohno-Machado, Staal A. Vinterbo, Griffin We...
—The peer-to-peer technology offers many advantages, but at the same time, it poses many novel challenges for the research community. Modern peer-to-peer systems are characterize...
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...