Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
This paper proposes a new approach for multicriteria optimization which aggregates the objective functions and uses a line search method in order to locate an approximate efficien...
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of membe...
We have developed and continue to enhance automated intelligent software that performs the tasks and decision making which now occurs by the personnel manning watch stations in the...
Robert Richards, Richard Stottler, Ben Ball, Cosku...
Phylogenomic analysis addresses the limitations of function prediction based on annotation transfer, and has been shown to enable the highest accuracy in prediction of protein mol...
Jake Gunn Glanville, Dan Kirshner, Nandini Krishna...