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BMCBI
2004
120views more  BMCBI 2004»
13 years 6 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...
BMCBI
2004
120views more  BMCBI 2004»
13 years 6 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones
BMCBI
2004
211views more  BMCBI 2004»
13 years 6 months ago
GenomeViz: visualizing microbial genomes
Background: An increasing number of microbial genomes are being sequenced and deposited in public databases. In addition, several closely related strains are also being sequenced ...
Rohit Ghai, Torsten Hain, Trinad Chakraborty
BMCBI
2004
125views more  BMCBI 2004»
13 years 6 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2004
88views more  BMCBI 2004»
13 years 6 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...