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BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
AINA
2006
IEEE
14 years 1 months ago
Partitioned optimization algorithms for multiple sequence alignment
Multiple sequence alignment is an important and difficult problem in molecular biology and bioinformatics. In this paper, we propose a partitioning approach that significantly impr...
Yixin Chen, Yi Pan, Juan Chen, Wei Liu, Ling Chen
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
14 years 24 days ago
Graph Alignments: A New Concept to Detect Conserved Regions in Protein Active Sites
: We introduce the novel concept of graph alignment, a generalization of graph isomorphism that is motivated by the commonly used multiple sequence alignments. Graph alignments and...
Nils Weskamp, Eyke Hüllermeier, Daniel Kuhn, ...
COCOA
2007
Springer
14 years 1 months ago
A Lagrangian Relaxation Approach for the Multiple Sequence Alignment Problem
Abstract. We present a branch-and-bound (bb) algorithm for the multiple sequence alignment problem (MSA), one of the most important problems in computational biology. The upper bou...
Ernst Althaus, Stefan Canzar
BIOINFORMATICS
2006
111views more  BIOINFORMATICS 2006»
13 years 7 months ago
Multiple Alignment of protein structures and sequences for VMD
Multiple Alignment is a new interface for performing and analyzing multiple protein structure alignments. It enables viewing levels of sequence and structure similarity on the ali...
John Eargle, Dan Wright, Zaida Luthey-Schulten