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BMCBI
2010
172views more  BMCBI 2010»
13 years 5 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
BMCBI
2010
219views more  BMCBI 2010»
13 years 5 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
BMCBI
2011
13 years 5 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...
BMCBI
2011
13 years 5 months ago
A Platform for Processing Expression of Short Time Series (PESTS)
Background: Time course microarray profiles examine the expression of genes over a time domain. They are necessary in order to determine the complete set of genes that are dynamic...
Anshu Sinha, Marianthi Markatou
BMCBI
2011
13 years 5 months ago
Logical Development of the Cell Ontology
Background: The Cell Ontology (CL) is an ontology for the representation of in vivo cell types. As biological ontologies such as the CL grow in complexity, they become increasingl...
Terrence F. Meehan, Anna Maria Masci, Amina Abdull...