Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...
Maria Luisa Chiusano, Nunzio D'Agostino, Alessandr...
Background: The rapid growth of protein-protein interaction (PPI) data has led to the emergence of PPI network analysis. Despite advances in high-throughput techniques, the intera...
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
The use of Chaos Game Representation (CGR) or its generalization, Universal Sequence Maps (USM), to describe the distribution of biological sequences has been found objectionable ...