In this paper we investigate the protein sequence design (PSD) problem (also known as the inverse protein folding problem) under the Canonical model 4 on 2D and 3D lattices [12, 25...
Piotr Berman, Bhaskar DasGupta, Dhruv Mubayi, Robe...
Modeling, characterization and analysis of biological shapes and forms are important in many computational biology studies. Shape representation challenges span the spectrum from s...
Bin Dong, Yu Mao, Ivo D. Dinov, Zhuowen Tu, Yongga...
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Background: Knowledge of the subcellular location of a protein is critical to understanding how that protein works in a cell. This location is frequently determined by the interpr...