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BMCBI
2010
152views more  BMCBI 2010»
15 years 6 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
BMCBI
2010
170views more  BMCBI 2010»
15 years 6 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2010
122views more  BMCBI 2010»
15 years 6 months ago
An overview of the CellML API and its implementation
Background: CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and...
Andrew K. Miller, Justin Marsh, Adam Reeve, Alan G...
BMCBI
2010
233views more  BMCBI 2010»
15 years 6 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
BIOSYSTEMS
2008
129views more  BIOSYSTEMS 2008»
15 years 6 months ago
Reconstruction of DNA sequences using genetic algorithms and cellular automata: Towards mutation prediction?
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...
Ch. Mizas, Georgios Ch. Sirakoulis, Vasilios A. Ma...
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