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BMCBI
2008
135views more  BMCBI 2008»
13 years 10 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
KAIS
2006
110views more  KAIS 2006»
13 years 10 months ago
Multi-step density-based clustering
Abstract. Data mining in large databases of complex objects from scientific, engineering or multimedia applications is getting more and more important. In many areas, complex dista...
Stefan Brecheisen, Hans-Peter Kriegel, Martin Pfei...
ISCI
2007
115views more  ISCI 2007»
13 years 9 months ago
Compressed histograms with arbitrary bucket layouts for selectivity estimation
Selectivity estimation is an important step of query optimization in a database management system, and multidimensional histogram techniques have proved promising for selectivity ...
Dennis Fuchs, Zhen He, Byung Suk Lee
BMCBI
2005
119views more  BMCBI 2005»
13 years 9 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2004
162views more  BMCBI 2004»
13 years 9 months ago
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant m
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...
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