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BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
SP
2008
IEEE
134views Security Privacy» more  SP 2008»
13 years 7 months ago
Discover gene specific local co-regulations from time-course gene expression data
Discovering gene co-regulatory relationships is one of most important research in DNA microarray data analysis. The problem of gene specific co-regulation discovery is to, for a p...
Ji Zhang, Qigang Gao, Hai H. Wang
RECOMB
2008
Springer
14 years 8 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
BMCBI
2004
124views more  BMCBI 2004»
13 years 7 months ago
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
James Lyons-Weiler, Satish Patel, Michael J. Becic...
BIBE
2003
IEEE
121views Bioinformatics» more  BIBE 2003»
14 years 27 days ago
Time Series Analysis of Gene Expression and Location Data
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcr...
Chen-Hsiang Yeang, Tommi Jaakkola