Background: DNA Microarray technology is an innovative methodology in experimental molecular biology, which has produced huge amounts of valuable data in the profile of gene expre...
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
Background: Microarray techniques are one of the main methods used to investigate thousands of gene expression profiles for enlightening complex biological processes responsible f...
Luca Corradi, Marco Fato, Ivan Porro, Silvia Scagl...
Image analysis is a crucial step in processing microarray data generated by gene expression studies, which have been used extensively in understanding the molecular mechanisms of ...
Yuhua Ding, Jacqueline Fairley, George J. Vachtsev...
—Normalization before clustering is often needed for proximity indices, such as Euclidian distance, which are sensitive to differences in the magnitude or scales of the attribute...