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CONSTRAINTS
2008
182views more  CONSTRAINTS 2008»
13 years 8 months ago
Constraint Programming in Structural Bioinformatics
Bioinformatics aims at applying computer science methods to the wealth of data collected in a variety of experiments in life sciences (e.g. cell and molecular biology, biochemistry...
Pedro Barahona, Ludwig Krippahl
RECOMB
2008
Springer
14 years 8 months ago
Constructing Treatment Portfolios Using Affinity Propagation
A key problem of interest to biologists and medical researchers is the selection of a subset of queries or treatments that provide maximum utility for a population of targets. For ...
Delbert Dueck, Brendan J. Frey, Nebojsa Jojic, Vla...
RECOMB
2010
Springer
14 years 3 months ago
Dense Subgraphs with Restrictions and Applications to Gene Annotation Graphs
Abstract. In this paper, we focus on finding complex annotation patterns representing novel and interesting hypotheses from gene annotation data. We define a generalization of th...
Barna Saha, Allison Hoch, Samir Khuller, Louiqa Ra...
CORR
2010
Springer
175views Education» more  CORR 2010»
13 years 8 months ago
Incorporating Side Information in Probabilistic Matrix Factorization with Gaussian Processes
Probabilistic matrix factorization (PMF) is a powerful method for modeling data associated with pairwise relationships, finding use in collaborative filtering, computational biolo...
Ryan Prescott Adams, George E. Dahl, Iain Murray
BMCBI
2006
85views more  BMCBI 2006»
13 years 8 months ago
SVM-based prediction of caspase substrate cleavage sites
Background: Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sit...
Lawrence J. K. Wee, Tin Wee Tan, Shoba Ranganathan