Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...
The success of mass spectrometry-based proteomics in emerging applications such as biomarker discovery and clinical diagnostics, is predicated substantially on its ability to achie...
Thodoros Topaloglou, Moyez Dharsee, Rob M. Ewing, ...
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
David A. Cairns, David N. Perkins, Anthea J. Stanl...
Background: The use of mass spectrometry as a proteomics tool is poised to revolutionize early disease diagnosis and biomarker identification. Unfortunately, before standard super...