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BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
Using a logical model to predict the growth of yeast
Background: A logical model of the known metabolic processes in S. cerevisiae was constructed from iFF708, an existing Flux Balance Analysis (FBA) model, and augmented with inform...
Ken E. Whelan, Ross D. King
BMCBI
2008
129views more  BMCBI 2008»
13 years 8 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
BMCBI
2008
166views more  BMCBI 2008»
13 years 8 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2008
124views more  BMCBI 2008»
13 years 8 months ago
Ontology-based, Tissue MicroArray oriented, image centered tissue bank
Background: Tissue MicroArray technique is becoming increasingly important in pathology for the validation of experimental data from transcriptomic analysis. This approach produce...
Federica Viti, Ivan Merelli, Andrea Caprera, Barba...
BMCBI
2008
100views more  BMCBI 2008»
13 years 8 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
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