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BMCBI
2010
125views more  BMCBI 2010»
13 years 10 months ago
In-silico prediction of blood-secretory human proteins using a ranking algorithm
Background: Computational identification of blood-secretory proteins, especially proteins with differentially expressed genes in diseased tissues, can provide highly useful inform...
Qi Liu, Juan Cui, Qiang Yang, Ying Xu
BMCBI
2010
152views more  BMCBI 2010»
13 years 10 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
BMCBI
2008
141views more  BMCBI 2008»
13 years 10 months ago
Discovering functional interaction patterns in protein-protein interaction networks
Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of ge...
Mehmet E. Turanalp, Tolga Can
BMCBI
2008
128views more  BMCBI 2008»
13 years 10 months ago
Efficient computation of absent words in genomic sequences
Background: Analysis of sequence composition is a routine task in genome research. Organisms are characterized by their base composition, dinucleotide relative abundance, codon us...
Julia Herold, Stefan Kurtz, Robert Giegerich
BMCBI
2010
133views more  BMCBI 2010»
13 years 10 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang