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BMCBI
2005
85views more  BMCBI 2005»
13 years 9 months ago
Processing methods for differential analysis of LC/MS profile data
Background: Liquid chromatography coupled to mass spectrometry (LC/MS) has been widely used in proteomics and metabolomics research. In this context, the technology has been incre...
Mikko Katajamaa, Matej Oresic
BMCBI
2005
115views more  BMCBI 2005»
13 years 9 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
BMCBI
2005
82views more  BMCBI 2005»
13 years 9 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
TJS
2008
105views more  TJS 2008»
13 years 9 months ago
Using a relational database for scalable XML search
XML is a flexible and powerful tool that enables information and security sharing in heterogeneous environments. Scalable technologies are needed to effectively manage the growing...
Rebecca Cathey, Steven M. Beitzel, Eric C. Jensen,...
BMCBI
2005
93views more  BMCBI 2005»
13 years 9 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
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