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ASE
2005
13 years 9 months ago
2005
Despite its well-recognized benefits, software reuse has not met its expected success due to technical, cognitive, and social difficulties. We have systematically analyzed the reu...
BMCBI
2005
13 years 9 months ago
2005
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
BMCBI
2005
13 years 9 months ago
2005
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
BMCBI
2005
2005
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
13 years 9 months ago
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
BMCBI
2005
13 years 9 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...