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BMCBI
2010
13 years 7 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
BMCBI
2010
13 years 7 months ago
2010
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
BMCBI
2010
13 years 7 months ago
2010
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
BMCBI
2010
13 years 7 months ago
2010
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
BMCBI
2010
13 years 7 months ago
2010
Background: Biological knowledge is represented in scientific literature that often describes the function of genes/ proteins (bioentities) in terms of their interactions (biointe...