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BMCBI
2010
117views more  BMCBI 2010»
13 years 2 months ago
Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities
Background: Shared-usage high throughput screening (HTS) facilities are becoming more common in academe as large-scale small molecule and genome-scale RNAi screening strategies ar...
Andrew N. Tolopko, John P. Sullivan, Sean D. Erick...
BMCBI
2010
108views more  BMCBI 2010»
13 years 2 months ago
Preferred analysis methods for Affymetrix GeneChips. II. An expanded, balanced, wholly-defined spike-in dataset
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
Qianqian Zhu, Jeffrey C. Miecznikowski, Marc S. Ha...
BMCBI
2010
123views more  BMCBI 2010»
13 years 2 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BMCBI
2010
160views more  BMCBI 2010»
13 years 2 months ago
eHive: An Artificial Intelligence workflow system for genomic analysis
Background: The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two week...
Jessica Severin, Kathryn Beal, Albert J. Vilella, ...
BMCBI
2011
13 years 2 months ago
CNV-WebStore: Online CNV Analysis, Storage and Interpretation
Background: Microarray technology allows the analysis of genomic aberrations at an ever increasing resolution, making functional interpretation of these vast amounts of data the m...
Geert Vandeweyer, Edwin Reyniers, Wim Wuyts, Liesb...