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BMCBI
2010
80views more  BMCBI 2010»
13 years 7 months ago
Sampling the conformation of protein surface residues for flexible protein docking
Background: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult on...
Patricia Francis-Lyon, Shengyin Gu, Joel Hass, Nin...
BMCBI
2010
189views more  BMCBI 2010»
13 years 6 months ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
FOCS
2010
IEEE
13 years 5 months ago
Boosting and Differential Privacy
Boosting is a general method for improving the accuracy of learning algorithms. We use boosting to construct improved privacy-preserving synopses of an input database. These are da...
Cynthia Dwork, Guy N. Rothblum, Salil P. Vadhan
BMCBI
2010
161views more  BMCBI 2010»
13 years 5 months ago
Application of Wavelet Packet Transform to detect genetic polymorphisms by the analysis of inter-Alu PCR patterns
Background: The analysis of Inter-Alu PCR patterns obtained from human genomic DNA samples is a promising technique for a simultaneous analysis of many genomic loci flanked by Alu...
Maurizio Cardelli, Matteo Nicoli, Armando Bazzani,...
BMCBI
2011
13 years 2 months ago
Removing Noise From Pyrosequenced Amplicons
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
Christopher Quince, Anders Lanzén, Russell ...