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BMCBI
2010
150views more  BMCBI 2010»
13 years 9 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
PAMI
2010
190views more  PAMI 2010»
13 years 7 months ago
OBJCUT: Efficient Segmentation Using Top-Down and Bottom-Up Cues
—We present a probabilistic method for segmenting instances of a particular object category within an image. Our approach overcomes the deficiencies of previous segmentation tech...
M. Pawan Kumar, Philip H. S. Torr, Andrew Zisserma...
BMCBI
2008
124views more  BMCBI 2008»
13 years 9 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2010
135views more  BMCBI 2010»
13 years 9 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2008
107views more  BMCBI 2008»
13 years 9 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....