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BMCBI
2011
12 years 11 months ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson
CSDA
2007
151views more  CSDA 2007»
13 years 7 months ago
Robust semiparametric mixing for detecting differentially expressed genes in microarray experiments
An important goal of microarray studies is the detection of genes that show significant changes in observed expressions when two or more classes of biological samples such as tre...
Marco Alfò, Alessio Farcomeni, Luca Tardell...
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Improving the prediction accuracy in classification using the combined data sets by ranks of gene expressions
Background: The information from different data sets experimented under different conditions may be inconsistent even though they are performed with the same research objectives. ...
Ki-Yeol Kim, Dong Hyuk Ki, Hei-Cheul Jeung, Hyun C...
BMCBI
2004
90views more  BMCBI 2004»
13 years 7 months ago
Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
Igor Dozmorov, Nicholas Knowlton, Yuhong Tang, Mic...