Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
nd: Biological pathways are a useful abstraction of biological concepts, and software tools to deal with pathway diagrams can help biological research. PathVisio is a new visualiz...
Martijn P. van Iersel, Thomas Kelder, Alexander R....
In many situations, a set of hard constraints encodes the feasible configurations of some system or product over which multiple users have distinct preferences. However, making su...
Object orientation and component-based development have both proven useful for the elaboration of open distributed systems. These paradigms are offered by the Creol language. Creo...
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...