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JCB
2008
106views more  JCB 2008»
13 years 8 months ago
Statistics of Random Protein Superpositions: p-Values for Pairwise Structure Alignment
Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...
James O. Wrabl, Nick V. Grishin
BCB
2010
140views Bioinformatics» more  BCB 2010»
13 years 3 months ago
Guiding belief propagation using domain knowledge for protein-structure determination
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
Ameet Soni, Craig A. Bingman, Jude W. Shavlik
APPROX
2007
Springer
87views Algorithms» more  APPROX 2007»
14 years 20 days ago
Stochastic Steiner Tree with Non-uniform Inflation
We study the Steiner Tree problem in the model of two-stage stochastic optimization with non-uniform inflation factors, and give a poly-logarithmic approximation factor for this pr...
Anupam Gupta, MohammadTaghi Hajiaghayi, Amit Kumar
SIGMOD
2011
ACM
241views Database» more  SIGMOD 2011»
12 years 11 months ago
Neighborhood based fast graph search in large networks
Complex social and information network search becomes important with a variety of applications. In the core of these applications, lies a common and critical problem: Given a labe...
Arijit Khan, Nan Li, Xifeng Yan, Ziyu Guan, Supriy...
NIPS
2004
13 years 10 months ago
Constraining a Bayesian Model of Human Visual Speed Perception
It has been demonstrated that basic aspects of human visual motion perception are qualitatively consistent with a Bayesian estimation framework, where the prior probability distri...
Alan Stocker, Eero P. Simoncelli