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BMCBI
2010
132views more  BMCBI 2010»
13 years 8 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
BMCBI
2010
146views more  BMCBI 2010»
13 years 8 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
BMCBI
2008
77views more  BMCBI 2008»
13 years 8 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Ranking the whole MEDLINE database according to a large training set using text indexing
Background: The MEDLINE database contains over 12 million references to scientific literature, ut 3/4 of recent articles including an abstract of the publication. Retrieval of ent...
Brian P. Suomela, Miguel A. Andrade
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 6 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick