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» On Complexity of Easy Predictable Sequences
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BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
WABI
2010
Springer
188views Bioinformatics» more  WABI 2010»
13 years 6 months ago
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs
Abstract. We present three heuristic strategies for folding RNA sequences into secondary structures including kissing hairpin motifs. The new idea is to construct a kissing hairpin...
Corinna Theis, Stefan Janssen, Robert Giegerich
BMCBI
2004
138views more  BMCBI 2004»
13 years 7 months ago
Constraint Logic Programming approach to protein structure prediction
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Alessandro Dal Palù, Agostino Dovier, Feder...
JMLR
2012
11 years 10 months ago
SpeedBoost: Anytime Prediction with Uniform Near-Optimality
We present SpeedBoost, a natural extension of functional gradient descent, for learning anytime predictors, which automatically trade computation time for predictive accuracy by s...
Alexander Grubb, Drew Bagnell
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...