The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
Human crooked neck protein (hcrn) containing 17 HAT or TPR repeats plays a role in pre-mRNA processing. Conserved residues in the TPR consensus sequence of 34 aa were found at hel...
Position-speci c scoring matrices are useful for representing and searching for protein sequence motifs. A sequence family can often be described by a group of one or more motifs,...
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...