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» On Compressibility of Protein Sequences
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RECOMB
2003
Springer
14 years 10 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
CSB
2005
IEEE
140views Bioinformatics» more  CSB 2005»
14 years 3 months ago
TPR Packing Analysis and 3D Modeling for the HAT Domain of Human Crooked Neck Protein
Human crooked neck protein (hcrn) containing 17 HAT or TPR repeats plays a role in pre-mRNA processing. Conserved residues in the TPR consensus sequence of 34 aa were found at hel...
Zhenglin Hou, Cunxi Wang, Odd-Arne Olsen
JCB
1998
84views more  JCB 1998»
13 years 10 months ago
Methods and Statistics for Combining Motif Match Scores
Position-speci c scoring matrices are useful for representing and searching for protein sequence motifs. A sequence family can often be described by a group of one or more motifs,...
Timothy L. Bailey, Michael Gribskov
BMCBI
2008
114views more  BMCBI 2008»
13 years 10 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
BMCBI
2006
137views more  BMCBI 2006»
13 years 10 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...