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» On Compressibility of Protein Sequences
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HAIS
2009
Springer
14 years 2 months ago
Incremental Kernel Machines for Protein Remote Homology Detection
Abstract. Protein membership prediction is a fundamental task to retrieve information for unknown or unidentified sequences. When support vector machines (SVMs) are associated with...
Lionel Morgado, Carlos Pereira
APBC
2003
138views Bioinformatics» more  APBC 2003»
13 years 11 months ago
A New Approach to Protein Structure and Function Analysis Using Semi-structured Databases
The development of high-throughput genome sequencing and protein structure determination techniques have provided researchers with a wealth of biological data. Integrated analysis...
William M. Shui, Raymond K. Wong, Stephen C. Graha...
ISMB
2000
13 years 11 months ago
Accelerating Protein Classification Using Suffix Trees
Position-specific scoring matrices have been used extensively to recognize highly conserved protein regions. We present a method for accelerating these searches using a suffix tre...
Bogdan Dorohonceanu, Craig G. Nevill-Manning
BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
13 years 10 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
BMCBI
2008
75views more  BMCBI 2008»
13 years 10 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...