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» On Compressibility of Protein Sequences
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BMCBI
2005
117views more  BMCBI 2005»
13 years 8 months ago
HmtDB, a Human Mitochondrial Genomic Resource Based on Variability Studies Supporting Population Genetics and Biomedical Researc
Background: Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information. Th...
Marcella Attimonelli, Matteo Accetturo, Monica San...
BMCBI
2004
151views more  BMCBI 2004»
13 years 8 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
SISAP
2010
IEEE
135views Data Mining» more  SISAP 2010»
13 years 7 months ago
Improving the similarity search of tandem mass spectra using metric access methods
In biological applications, the tandem mass spectrometry is a widely used method for determining protein and peptide sequences from an ”in vitro” sample. The sequences are not...
Jiri Novák, Tomás Skopal, David Hoks...
BMCBI
2011
13 years 3 months ago
Analysis on the reconstruction accuracy of the Fitch method for inferring ancestral states
Background: As one of the most widely used parsimony methods for ancestral reconstruction, the Fitch method minimizes the total number of hypothetical substitutions along all bran...
Jialiang Yang, Jun Li, Liuhuan Dong, Stefan Gr&uum...
BMCBI
2011
13 years 8 days ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg