Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...
A number of bioinformatics tools use regular expression (RE) matching to locate protein or DNA sequence motifs that have been discovered by researchers in the laboratory. For exam...
Amine Heddad, Markus Brameier, Robert M. MacCallum