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» On Compressibility of Protein Sequences
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BMCBI
2008
176views more  BMCBI 2008»
13 years 7 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Compressed Pattern Matching in DNA Sequences
We propose derivative Boyer-Moore (d-BM), a new compressed pattern matching algorithm in DNA sequences. This algorithm is based on the BoyerMoore method, which is one of the most ...
Lei Chen, Shiyong Lu, Jeffrey L. Ram
VLDB
2002
ACM
184views Database» more  VLDB 2002»
14 years 8 months ago
Database indexing for large DNA and protein sequence collections
Our aim is to develop new database technologies for the approximate matching of unstructured string data using indexes. We explore the potential of the suffix tree data structure i...
Ela Hunt, Malcolm P. Atkinson, Robert W. Irving
BMCBI
2008
57views more  BMCBI 2008»
13 years 7 months ago
A novel method for high accuracy sumoylation site prediction from protein sequences
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
Jialin Xu, Yun He, Boqin Qiang, Jiangang Yuan, Xia...